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In-Silico Analysis of Proteins

Celebrating the 20th anniversary of Swiss-Prot

July 30 - August 04, 2006 : Fortaleza, Brazil

Poster #RP131

Database of Venon of Apoidea (Hymenoptera) and medicinal plants associated.

Daniel M. M. Jorge*, Renato D. Puga*, Andreimar M. Soares**, Ademilson E. E. Soares*, Silvana Giuliatti*

*Faculty of Medicine of Ribeirao Preto - USP, Ribeirao Preto, Sao Paulo, Brazil; **Faculty of Science of Pharmacy of Ribeirao Preto - USP, Ribeirao Preto, Sao Paulo, Brazil

Bees are one of the most important insect in the world and there are important in medicine, agriculture and ecology. Sequencing of DNA and protein of bee increase the knowledge about this group and almost all sequence is deposited in GenBank. In May 2006 GenBank contains around 67,134 of DNA and 10,346 protein sequences of bee, although a small number represents venom. Some medicinal plants can be used as anti-poisons for great number of different venom, include bee venom. In Brazil, there is great number of medicinal plants, in spite of small number are associated with anti-poisons of bee. Therefore we proposed a database that integrates scientific data of anti-poison medicinal plants and bee poisons. The aims of this work are search and organize all information in a database. Sequences of DNA and protein are collected from GenBank, and are updated frequently. All sequences obtained are divided per species and per type of venom. and information of anti-poisons will be correlate with correspondence protein. The database will be developed in MySQL and web interface will be managed with Drupal. Scripts are being implemented in PHP and Perl languages. This database will contribute to bee venom studies.